Use of betahistine or cinnarizine in Ménière’s disease, vertigo disorders or tinnitus

Disorders of the inner ear can cause symptoms such as vertigo, tinnitus, and hearing loss. Betahistine and cinnarizine with or without dimenhydrinate are used in people with vertigo disorders including Ménière’s disease. These medicines are reimbursed by the compulsory health insurance scheme, but their clinical efficacy is unclear. This report evaluates the efficacy and safety of the treatments in patients with Ménière’s disease, vertigo disorders or tinnitus, as well as cost-effectiveness and the budgetary impact.